Metformin improved outcomes in patients with type 2 diabetes mellitus and sepsis in hospital settings. #diabetes
A retrospective cohort study compared 90-day mortality in diabetic patients with sepsis. The study reported that metformin use was associated with a decrease in risk. Within a total of 2,691 patients subjected to propensity score-matching at a 1:4 ratio, exposure to metformin was associated with decreased 90-day mortality (11.9%), reduced severe acute kidney injury (50%), fewer Major Adverse Kidney Events at one year, and increased renal recovery (95%)
The study was based on data from Patients admitted to ICUs in 16 hospitals in Pennsylvania.
Metformin improved outcomes in patients with type 2 diabetes mellitus and sepsis in hospital settings