Mucormycosis is a rare but potentially life-threatening fungal infection. The condition occurs when a person inhales or comes into contact with spores of fungi from the environment, which can then infect the body.
Mucormycosis can affect different body parts, including the sinuses, lungs, skin, gastrointestinal tract, and central nervous system.
The symptoms and severity of the infection depend on the site of infection. In the sinuses, mucormycosis can cause facial pain, headache, fever, congestion, and discharge. Left untreated, it can spread to the eyes and brain, causing vision loss, double vision, and other neurological symptoms. In the lungs, mucormycosis can cause cough, chest pain, fever, and shortness of breath. In severe cases, it can lead to respiratory failure and death. In the skin, mucormycosis can cause redness, swelling, and pain, followed by the development of dark, necrotic lesions.
Mucormycosis is more common in people with weakened immune systems, such as those with uncontrolled diabetes, cancer, HIV/AIDS, or those who have received organ transplants or immunosuppressive medications.
It can also occur in healthy people who have had a traumatic injury or surgery.
Treatment for mucormycosis usually involves antifungal medications, such as amphotericin B, posaconazole, or isavuconazole, and surgery to remove infected tissue. The earlier the treatment starts, the better the chances of a good outcome.