Alterations in the brain and human aging

Aging is an inevitable facet of life, and yet the biology underlying this actuality remains poorly understood. Even though it affects every organ in the body, ageing cannot be explained by a single pathway, and it is unclear what exactly causes the considerable changes in the brain. Since declining mortality rates have boosted life expectancy—which […]

Intake of an FDA-approved medication, according to researchers, slows the progression of the condition in an Alzheimer’s disease model

The study, recently published in Science Translational Medicine, investigates how niacin modulates microglia response to amyloid plaques in an Alzheimer’s disease animal model. The study’s principal investigators were Miguel Moutinho, PhD, a postdoctoral researcher in anatomy, cell biology, and physiology, and Gary Landreth, PhD, the Martin Professor of Alzheimer’s Research. “This study identifies a potential novel […]

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