In light of the possibility of serious consequences, such as hospitalisation and death, the FDA stated that it is investigating the risk of severe hypocalcemia among dialysis patients using denosumab (Prolia). The FDA alluded to interim findings from denosumab maker Amgen’s ongoing safety trial, which revealed an elevated risk of hypocalcemia in patients with severe […]
Increased levels of certain chemokines in the blood are associated with an increased risk of hip fracture in men
In new research published in the Journal of Bone and Mineral Research, elevated blood levels of a certain chemokine, or small signaling protein, that promotes osteoclast formation were linked with a higher risk of hip fracture in men. Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts. […]
