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Thu. Apr 18th, 2024

Excessive weight gain during pregnancy increases the risk of cardiovascular disease

Cardiovascular disease is the deadliest worldwide, according to IHME estimates on the Global Burden of Disease. 

Many different cardiac disorders are referred to as “heart disease.” Coronary artery disease, which can cause a heart attack, is the most common type of heart disease.

Smoking, high blood cholesterol, and high blood pressure are a some of the things that can make you more susceptible to heart disease. According to a recent study that was peer-reviewed and published in the Journal of Women’s Health, midlife cardiovascular risk was higher among pregnant women who had large prenatal weight gain.

The atherosclerotic cardiovascular disease (ASCVD) risk score and a measurement of the inflammatory biomarker C-reactive protein (CRP) were the two key metrics Franya Hutchins, Ph.D., and colleagues utilized to assess a woman’s risk of developing cardiovascular disease. Over a 20-year period, the researchers evaluated these characteristics at baseline and ten follow-up visits.

“In the model including confounders and midlife abdominal obesity, excessive gestational weight gain remained associated with a 9.1% higher ASCVD score,” stated the investigators. “In this group of women, a history of excessive gestational ( pregnancy ) weight gain was associated with a small but statistically significant higher ASCVD score and a moderate, statistically significant higher mean CRP level into midlife,” says Journal of Women’s Health Editor-in-Chief Susan G. Kornstein, MD.

A baseline ASCVD risk score that was 29.6 percent higher in individuals with a history of significant prenatal weight gain was found. A baseline CRP level that was 89.2 percent higher was linked to excessive gestational weight gain during pregnancy.

Excessive prenatal weight increase was still linked to a 31.5 percent higher mean CRP after accounting for confounders and midlife abdominal obesity.

By Editor

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